Prognostic role of soluble suppression of tumorigenicity-2 on cardiovascular mortality in outpatients with heart failure

GÜL İ., Yucel O., ZARARSIZ A., DEMİRPENÇE Ö., YÜCEL H., ZORLU A., ...More

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.18, no.3, pp.200-205, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.14744/anatoljcardiol.2017.7741
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.200-205
  • Keywords: soluble suppression of tumorigenicity-2, heart failure, cardiovascular mortality, FAMILY-MEMBER ST2, AMBULATORY PATIENTS, SERUM-LEVELS, BIOMARKERS, RECEPTOR, DISEASE, ASSOCIATION
  • Dokuz Eylül University Affiliated: No

Abstract

Objective: Soluble suppression of tumorigenicity-2 (sST2), a member of the interleukin 1 receptor family, is increased in mechanical stress conditions and is produced by cardiomyocytes and cardiac fibroblasts. Elevated sST2 level is associated with the prognosis of acute coronary syndrome, pulmonary arterial hypertension, and acute and chronic heart failure (HF). In this study, we aimed to investigate the relationship between sST2 levels and cardiovascular mortality in outpatients with HF.