Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

Gelal, AYŞE; Balkan, D; Ozzeybek, D; Kaplan, YC; Gurler, SELMA; Guven, H; Benowitz, NL

doi:10.1007/s00228-004-0847-8

Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

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Gelal A., Balkan D., Ozzeybek D., Kaplan Y., Gurler S., Guven H., ...More

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.60, no.11, pp.785-790, 2005 (SCI-Expanded)

Publication Type: Article / Article
Volume: 60 Issue: 11
Publication Date: 2005
Doi Number: 10.1007/s00228-004-0847-8
Journal Name: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.785-790
Keywords: felodipine, menthol, monoterpenes, essential oils, PEPPERMINT OIL, IN-VITRO, DISPOSITION, KINETICS
Dokuz Eylül University Affiliated: Yes

Abstract

Objectives: The present study was undertaken to determine whether menthol affects the metabolism of and pharmacological responses to the calcium channel antagonist felodipine in people.