Pancreas, vol.27, no.3, pp.247-52, 2003 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
acute pancreatitis, deferoxamine, meropenem, secondary infections, PLATELET-ACTIVATING-FACTOR, NECROTIZING PANCREATITIS, ANTIBIOTIC-PROPHYLAXIS, SURGICAL-TREATMENT, OXIDATIVE STRESS, TISSUE, RATS, PENETRATION, NEUTROPHILS, NECROSIS
Dokuz Eylül University Affiliated:
Introduction: Recent data from the experimental clinical studies suggest that antibiotics having good penetration to pancreas may reduce mortality by preventing pancreatic infection, which is the most important prognostic factor in acute pancreatitis (AP). Deferoxamine is an active free oxygen radical scavenger, which has been shown to have a protective role in development of acute pancreatitis.