Effects of APOE, ACE, PICALM, and CYP2D6 Gene Variants on Alzheimer's Disease

Oz O., YENER G., BORA E., ÇANKAYA T., ATAMAN E., Ercal D., ...Daha Fazla

CURRENT PSYCHIATRY RESEARCH AND REVIEWS, cilt.17, sa.2, ss.127-136, 2021 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/2666082217666210907104004
  • Dergi Adı: CURRENT PSYCHIATRY RESEARCH AND REVIEWS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, Psycinfo
  • Sayfa Sayıları: ss.127-136
  • Anahtar Kelimeler: Early-onset Alzheimer's disease, late-onset Alzheimer's disease, APOE, PICALM, ACE, CYP2D6, polymorphism, GENOME-WIDE ASSOCIATION, IDENTIFIES VARIANTS, DEMENTIA, RECOMMENDATIONS, POLYMORPHISM, PREVALENCE, DIAGNOSIS, DONEPEZIL, CLU
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Alzheimer's disease is a multifactorial, neurodegenerative disease which is considered the most common cause of dementia. It is divided into two subtypes based on the age of onset: Early- Onset Alzheimer's Disease (EOAD) and Late-Onset Alzheimer's Disease ( LOAD).