Weekly irinotecan in patients with metastatic colorectal cancer failing 5-fluorouracil-based chemotherapy: Efficacy and prognostic factors

Karaoglu A., Yalcin S., Tekuzman G., Kars A., Celik I., Guler N., ...More

TUMORI, vol.89, no.2, pp.141-145, 2003 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1177/030089160308900207
  • Journal Name: TUMORI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.141-145
  • Keywords: colorectal cancer, irinotecan, recurrent, PHASE-II, CAMPTOTHECIN, CPT-11, TRIAL, PHARMACOKINETICS, FLUOROURACIL, CARCINOMA, SN-38
  • Dokuz Eylül University Affiliated: No

Abstract

Aims and background: We evaluated the efficacy and tolerability of weekly irinotecan as a second-line treatment in patients with colorectal cancer failing 5-fluorouracil-based chemotherapy and searched for predictive and prognostic factors.