beta-catenin gene mutation in invasive ductal breast cancer


Kizildag S., Zengel B., Vardar E., Sakizli M.

JOURNAL OF BUON, vol.13, no.4, pp.533-536, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 4
  • Publication Date: 2008
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.533-536
  • Keywords: breast cancer, beta-catenin, cyclin D1, localization, mutation, EXON 3, COLORECTAL-CANCER, CTNNB1 MUTATIONS, CELL-ADHESION, WILMS-TUMORS, CARCINOMAS, ACTIVATION, TARGET, EXPRESSION, PATHWAY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: Aberrant accumulation of beta-catenin plays an important role in a variety of human neoplasms. In this study we analyzed the somatic mutations of the beta-catenin gene and the immunohistochemical localization of beta-catenin and cyclin D1 in invasive ductal breast cancer.