beta-catenin gene mutation in invasive ductal breast cancer
JOURNAL OF BUON, cilt.13, sa.4, ss.533-536, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 4
- Basım Tarihi: 2008
- Dergi Adı: JOURNAL OF BUON
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.533-536
- Anahtar Kelimeler: breast cancer, beta-catenin, cyclin D1, localization, mutation, EXON 3, COLORECTAL-CANCER, CTNNB1 MUTATIONS, CELL-ADHESION, WILMS-TUMORS, CARCINOMAS, ACTIVATION, TARGET, EXPRESSION, PATHWAY
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Purpose: Aberrant accumulation of beta-catenin plays an important role in a variety of human neoplasms. In this study we analyzed the somatic mutations of the beta-catenin gene and the immunohistochemical localization of beta-catenin and cyclin D1 in invasive ductal breast cancer.