POSSIBLE THERAPEUTIC ROLE OF CHOLINERGIC AGONISTS ON COVID-19 RELATED INFLAMMATORY RESPONSE
JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.5, no.1, pp.102-108, 2021 (ESCI)
- Publication Type: Article / Article
- Volume: 5 Issue: 1
- Publication Date: 2021
- Doi Number: 10.30621/jbachs.869857
- Journal Name: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
- Journal Indexes: Emerging Sources Citation Index (ESCI)
- Page Numbers: pp.102-108
- Keywords: Cholinomimetic drugs, COVID-19, SARS-CoV-2, Cytokine Storm
- Dokuz Eylül University Affiliated: Yes
Abstract
Severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) or coronavirus infectious disease (COVID-19) outbreak is continued to spread all over the world recently with the high mortality and morbidity rates. It is also known well COVID-19 is leading causes of acute lung injury and acute respiratory distress syndrome (ARDS), sepsis and multiorgan failure. Current treatment of COVID-19, includes different strategies targeting preventing viral replication or treating secondary infections and decreasing exaggerated immune response. Although antiviral, antimicrobial, immunomodulatory agents including anti-cytokines and glucocorticoids have been currently applied, there is lack of a specific treatment for COVID-19. In this review, possible therapeutic roles of cholinomimetic drugs in the control of COVID-19 related inflammation is discussed.