POSSIBLE THERAPEUTIC ROLE OF CHOLINERGIC AGONISTS ON COVID-19 RELATED INFLAMMATORY RESPONSE


Baris E., Arici M. A.

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, cilt.5, sa.1, ss.102-108, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.30621/jbachs.869857
  • Dergi Adı: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.102-108
  • Anahtar Kelimeler: Cholinomimetic drugs, COVID-19, SARS-CoV-2, Cytokine Storm
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) or coronavirus infectious disease (COVID-19) outbreak is continued to spread all over the world recently with the high mortality and morbidity rates. It is also known well COVID-19 is leading causes of acute lung injury and acute respiratory distress syndrome (ARDS), sepsis and multiorgan failure. Current treatment of COVID-19, includes different strategies targeting preventing viral replication or treating secondary infections and decreasing exaggerated immune response. Although antiviral, antimicrobial, immunomodulatory agents including anti-cytokines and glucocorticoids have been currently applied, there is lack of a specific treatment for COVID-19. In this review, possible therapeutic roles of cholinomimetic drugs in the control of COVID-19 related inflammation is discussed.