Allele frequencies of dopamine D4 receptor gene (DRD4) and Catechol-O-methyltransferase (COMT) Val158Met polymorphism are associated with methylphenidate response in adolescents with attention deficit/hyperactivity disorder: a case control preliminary study

AKAY, AYNUR; ERESEN YAZICIOĞLU, ÇİĞDEM; ALŞEN GÜNEY, SEVAY; Erkuran, Handan; KIZILDAĞ, SEFA; BAYKARA, HÜSEYİN; Ozyurt, Gonca; Kadicesme, Sebnem; Miral, Suha; Emiroglu, Neslihan

doi:10.1080/24750573.2017.1418134

Allele frequencies of dopamine D4 receptor gene (DRD4) and Catechol-O-methyltransferase (COMT) Val158Met polymorphism are associated with methylphenidate response in adolescents with attention deficit/hyperactivity disorder: a case control preliminary study

AKAY A., ERESEN YAZICIOĞLU Ç., ALŞEN GÜNEY S., Erkuran H. O., KIZILDAĞ S., BAYKARA H. B., ...Daha Fazla

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.28, sa.2, ss.177-184, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 28 Sayı: 2
Basım Tarihi: 2018
Doi Numarası: 10.1080/24750573.2017.1418134
Dergi Adı: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.177-184
Anahtar Kelimeler: Attention deficit/hyperactivity disorder, adolescents, catechol-O-methyltransferase gene (COMT), dopamine D4 receptor gene (DRD4), methylphenidate, clinical global impression (CGI)
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

OBJECTIVES: In this study, it was aimed to analyse the relationship between clinical improvement in adolescents with attention deficit/hyperactivity disorder (ADHD) and the presence of allele frequencies of dopamine D4 receptor (DRD4), and Val158Met polymorphism of catechol-O-methyltransferase (COMT) genes.