Automated patient-specific classification of long-term Electroencephalography


Kiranyaz S., İNCE T., Zabihi M., İNCE D.

JOURNAL OF BIOMEDICAL INFORMATICS, cilt.49, ss.16-31, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jbi.2014.02.005
  • Dergi Adı: JOURNAL OF BIOMEDICAL INFORMATICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.16-31
  • Anahtar Kelimeler: EEG classification, Seizure event detection, Evolutionary classifiers, Morphological filtering, FEATURE-SELECTION, EPILEPTIC SEIZURES, MUTUAL INFORMATION, ALGORITHM, RELEVANCE, ONSET
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

This paper presents a novel systematic approach for patient-specific classification of long-term Electroencephalography (EEG). The goal is to extract the seizure sections with a high accuracy to ease the Neurologist's burden of inspecting such long-term EEG data. We aim to achieve this using the minimum feedback from the Neurologist. To accomplish this, we use the majority of the state-of-the-art features proposed in this domain for evolving a collective network of binary classifiers (CNBC) using multi-dimensional particle swarm optimization (MD PSO). Multiple CNBCs are then used to form a CNBC ensemble (CNBC-E), which aggregates epileptic seizure frames from the classification map of each CNBC in order to maximize the sensitivity rate. Finally, a morphological filter forms the final epileptic segments while filtering out the outliers in the form of classification noise. The proposed system is fully generic, which does not require any a priori information about the patient such as the list of relevant EEG channels. The results of the classification experiments, which are performed over the benchmark CHB-MIT scalp long-term EEG database show that the proposed system can achieve all the aforementioned objectives and exhibits a significantly superior performance compared to several other state-of-the-art methods. Using a limited training dataset that is formed by less than 2 min of seizure and 24 min of non-seizure data on the average taken from the early 25% section of the EEG record of each patient, the proposed system establishes an average sensitivity rate above 89% along with an average specificity rate above 93% over the test set. (C) 2014 Elsevier Inc. All rights reserved.