The Role of the Basal Core Promoter (BCP) and Precore Codon 28 Mutations in the Treatment Response to the Pegylated Interferon
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, vol.20, no.1, pp.19-22, 2014 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 20 Issue: 1
- Publication Date: 2014
- Doi Number: 10.4274/vhd.74946
- Journal Name: VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
- Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Page Numbers: pp.19-22
- Keywords: Hepatitis B, pegylated interferon, precore mutations
- Open Archive Collection: AVESIS Open Access Collection
- Dokuz Eylül University Affiliated: No
Abstract
Objective: Pegylated interferon has an important place in chronic hepatitis treatment and there are many factors affecting treatment response. Among these factors, studies on viral genomic mutations increase recently. In this study we aimed to determine the effects of precore and basal core promoter (BCP) mutations on the response to peg-interferon treatment treatment in patients received interferon treatment with the diagnosis of chronic hepatitis B.