The Role of the Basal Core Promoter (BCP) and Precore Codon 28 Mutations in the Treatment Response to the Pegylated Interferon

Kose, ŞÜKRAN; Senger, Suheyla; Cavdar, Gulsun; Adar, Pelin

doi:10.4274/vhd.74946

The Role of the Basal Core Promoter (BCP) and Precore Codon 28 Mutations in the Treatment Response to the Pegylated Interferon

Kose Ş., Senger S. S., Cavdar G., Adar P.

VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.20, sa.1, ss.19-22, 2014 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 1
Basım Tarihi: 2014
Doi Numarası: 10.4274/vhd.74946
Dergi Adı: VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.19-22
Anahtar Kelimeler: Hepatitis B, pegylated interferon, precore mutations
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objective: Pegylated interferon has an important place in chronic hepatitis treatment and there are many factors affecting treatment response. Among these factors, studies on viral genomic mutations increase recently. In this study we aimed to determine the effects of precore and basal core promoter (BCP) mutations on the response to peg-interferon treatment treatment in patients received interferon treatment with the diagnosis of chronic hepatitis B.