JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.7, pp.94-102, 2023 (Peer-Reviewed Journal)
Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in
pregnancies after IVF treatment and to evaluate the factors that reduce this risk.
Material and Methods: This retrospective cohort study was conducted using the medical records of
pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The
data were obtained from medical records and phone interviews. Univariate and multivariate logistic
regression analyses were performed.
Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk
of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age
group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second
IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95%
CI = 1.07–11.23, p= .038).
Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after
Keywords: Gestational diabetes mellitus, in vitro fertilization, risk factors