Akademik Veri Yönetim Sistemi
SICSSO CONGRESS 2024, GROSSETO/ITLAY, Florence, İtalya, 27 - 29 Haziran 2024, ss.90, (Tam Metin Bildiri)
| Purpose | |
| To evaluate the peripapillary retinal nerve fiber layer, macular and peripapillary microvascularity in eyes with keratoconus (KC) using optical coherence tomography (OCT) and OCT Angiography (OCTA). | |
| Methods | |
| Patients who are under 15 years of age, who had undergone eye surgery for reasons other than KC, have spherical equivalents above ±20 D, systemic hypertension, migraine and vasculopathy, ocular hypertension, cloudiness covering the optic axis, and low-quality images with artifacts were not included in the study. Enrolled subjects underwent Scheimpflug corneal tomography (Pentacam), macular and optic nerve head swept-source OCT (SS-OCT) with 3D wide glaucoma module for peripapillary radial nerve fiber layer (RNFL) thickness measurement, and SS-OCTA 6x6 scans for macular and optic nerve head measurements. The central corneal thickness (CCT) in corneal tomography; the central macula (CMT) and choroidal (CT) thicknesses and peripapillary RNFL thicknesses in SS-OCT were compared. The vessel density (VD) at macular superficial capillary plexus (mSCP), deep capillary plexus (mDCP), choriocapillaris (mCC), and nerve radial peripapillary capillary plexus (nRPCP) were calculated with SS-OCTA. | |
| Results | |
| Overall, 30 KC eyes (Group 1) and an equal number of age and axial-length-matched control eyes (Group 2) were included in the analysis. Eyes with KC were classified as stage 1 (n=6), stage 2 (n=14), stage 3 (n=9), and stage 4 (n=1). Among 30 KC eyes, 17 (56.7%) had corneal-cross linking surgery before. KC eyes displayed a thinner CCT (446.40±55.98 vs 542.87±27.66), nRPCP VD (42.70±7.31 vs 47.93±3.50) but a thicker central CT (243.87±53.34 vs 203.83±26.85) (p≤0.001). The mDCP, mSCP, mCC VD in KC eyes were thinner nasally and globally, thicker temporally, as compared with healthy controls(p<0.05). Interestingly, mDCP, mSCP and mCC in superior and inferior quadrants were similar in both groups (p>0.05). In this study, peripapillary RNFL thickness was found to be similar in both groups in all quadrants (p>0.05, for all). | |
| Conclusions | |
| These findings confirm that KC is associated with altered blood supply in the macular and lamina cribrosa regions. | |