SURGICAL INFECTIONS, cilt.16, sa.5, ss.558-565, 2015 (SCI-Expanded)
Purpose: The aim of this retrospective study was to evaluate the efficacy of vacuum-assisted closure (VAC) and GranuFoam Silver((R)) dressing (KCI, San Antonio, TX) compared with conventional GranuFoam((R)) dressing in the management of diabetic foot ulcers. Patients and Methods: Twenty-one consecutive patients treated with conventional or silver-coated foam dressing were reviewed retrospectively. The wound duration was 6mo. Group 1 (n=10) received conventional foam dressing (GranuFoam) and group 2 (n=11) received silver-coated foam dressing (GranuFoam Silver). The wound surface area, duration of treatment, bacteriology, and recurrence were compared between the groups. The mean age of the patients was 61.7010.52y in group 1 and 67.2711.28y in group 2. Results: In group 1, the average surface area of the wounds was 45.30 +/- 46.96cm(2) and 18.40 +/- 23.48cm(2) in the pre-treatment and post-treatment periods, respectively. There was a statistically significant difference between two measurements (p=0.005). Average duration of the treatment was 25.50 +/- 27.13d in this group. In group 2, average surface area of the wounds in the pre-treatment and post-treatment periods were 41.55 +/- 36.03cm(2) and 7.64 +/- 3.91cm(2), respectively. There was a statistically significant difference between two measurements (p=0.003). Average duration of the treatment was 10.09 +/- 3.51d in this group. The patients treated with silver-impregnated polyurethane foam dressing had reduced recurrence (2 vs. 7 wounds, p=0.030) and increased number of the culture-negative cases at the end of the treatment. Conclusion: With the results of the study, it was concluded that VAC GranuFoam silver dressing can be superior to conventional GranuFoam dressing in reducing the recurrence rate of infected diabetic foot ulcers.