Evaluation of MicroRNA Expressions in Ovarian Cancer

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Yavuzsen H. T., Yavuzşen T., Altun Z. S., Diniz Ünlü G., Aktaş T., Ayaz D., ...More

2nd International Medical Congress of Izmir Democracy University, Healty Aging anbd Aging-Associated Diseases, IMCUDU 2020 , İzmir, Turkey, 17 - 19 December 2020, vol.580, no.580, pp.580

  • Publication Type: Conference Paper / Full Text
  • Volume: 580
  • City: İzmir
  • Country: Turkey
  • Page Numbers: pp.580
  • Dokuz Eylül University Affiliated: Yes

Abstract

Ovarian cancer is the fifth most common death cause from cancer among women. Currently, gynecological examination, evaluation with ultrasound and serum measurements of tumor markers such as CA-125 is used for the diagnosis and monitorization of treatment for ovarian cancer. However, there is an intense need for new biomarkers that can guide the diagnosis and treatment of the disease. MicroRNAs (miRNAs), short, non-coding RNAs, are stabilizing endogenous RNAs which may prove to be particularly useful biomarkers in cancer. The aim of this study is to determine the relationship between microRNA expressions with clinical and histopathological findings in ovarian cancer to evaluate its potential biomarker in ovarian cancer.