The effect of alendronate sodium on carotid artery intima-media thickness and lipid profile in women with postmenopausal osteoporosis


CELİLOĞLU M., Aydin Y., BALCI P., Kolamaz T.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, vol.16, no.4, pp.689-693, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1097/gme.0b013e318194cafd
  • Journal Name: MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.689-693
  • Keywords: Alendronate, Atherosclerosis, Lipids, AORTIC CALCIFICATION, CARDIOVASCULAR-DISEASE, APOLIPOPROTEIN-B, BONE-RESORPTION, BISPHOSPHONATES, ATHEROSCLEROSIS, ETIDRONATE, THERAPY, RISK, ACCUMULATION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Observational and experimental studies support that osteoporosis and atherosclerosis are two related phenomena. The aim of the present study was to investigate the probable effect of alendronate sodium, which is used in the treatment of osteoporosis, on carotid artery intima-media thickness (IMT), the lipid profile, and apolipoprotein A-I (ApoA-I) and apolipoprotein B (ApoB) levels, which are known to have a role in the atherosclerotic process.