Analysis of Biochemical Markers in Diabetic Hemodialysis Patients on Conventional or Intensive Insulin Therapy
TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, cilt.18, sa.1, ss.15-19, 2009 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 1
- Basım Tarihi: 2009
- Dergi Adı: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.15-19
- Anahtar Kelimeler: Diabetes, Dialysis, Insulin therapy
- Dokuz Eylül Üniversitesi Adresli: Hayır
Özet
OBJECTIVE: The objective of this study was to compare intensive and conventional insulin therapies with regards to HbA1c, serum lipids, and other biochemical markers. METHODS: This was a retrospective study investigating data from 44 insulin-dependent diabetic hemodialysis patients followed in our hemodialysis unit. Fifteen of the patients were on conventional therapy and 29 were on intensive therapy. RESULTS: Of the patients 34% were women, the mean age was 60 +/- 10 years, duration of diabetes 18 +/- 8 years and dialysis duration 3 +/- 2 years. Weight gain between dialysis sessions was 2570 +/- 768 g and dry weight was 64.6 +/- 1.3 kg. There was no significant difference between the two treatments in terms of HbA1c, CRP, hemoglobin, urea, creatinine, uric acid, albumin and electrolytes (p>0.05). Although total cholesterol and triglyceride levels were lower in the intensive treatment group than that conventional treatment grap the difference was not statistically significant (p>0.05). LDL and HDL levels were not statistically different between the study groups (p>0.05). CONCLUSIONS: There was no statistically significant difference between conventional and intensive insulin treatments in terms of HbA1c or other biochemical markers.