Evaluation of neutrophil gelatinase-associated lipocalin in pediatric patients with acute rotavirus gastroenteritis and dehydration.

Celik T., ALTEKİN E., Isguder R., Kenesari Y., DUMAN M., ARSLAN N.

Italian journal of pediatrics, cilt.39, ss.52, 2013 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1186/1824-7288-39-52
  • Dergi Adı: Italian journal of pediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.52
  • Anahtar Kelimeler: Acute kidney injury, Children, Dehydration, Neutrophil gelatinase-asssociated lipocalin
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Dehydration caused by acute rotavirus gastroenteritis is a frequent finding in pediatric patients. The most important treatment modality in these patients is recognising and treating dehydration, electrolyte imbalance and acute kidney injury. Neutrophil gelatinase-asssociated lipocalin (NGAL) is used widely as a biomarker for the diagnosis of acute or chronic renal injury in numerous clinical studies. It is recognized as an early marker of acute renal failure before the elevation of routine biochemical tests such as creatinine. The aim of this study is to investigate the plasma and urine NGAL concentrations in mildly or moderately dehydrated patients with acute rotavirus gastroenteritis.