Tamoxifen as First-line Treatment in a Premenarchal Girl with Juvenile Breast Hypertrophy

DEMİR, KORCAN; Unuvar, Tolga; Eren, Sanem; ABACI, AYHAN; BÖBER, ECE

doi:10.1016/j.jpag.2009.11.003

Tamoxifen as First-line Treatment in a Premenarchal Girl with Juvenile Breast Hypertrophy

DEMİR K., Unuvar T., Eren S., ABACI A., BÖBER E.

Journal of Pediatric and Adolescent Gynecology, cilt.23, sa.5, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 5
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.jpag.2009.11.003
Dergi Adı: Journal of Pediatric and Adolescent Gynecology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Juvenile breast hypertrophy is uncommon and is characterized by excessive breast enlargement in the peripubertal period. The clinical entity is thought to result from increased sensitivity of mammary tissue to normal levels of circulating hormones. Case: Here, we report a female patient, aged 12 years and 6 months, suffering from juvenile breast hypertrophy, who presented at the third month of symptoms and benefited from tamoxifen treatment. Comments: In experienced clinics, use of tamoxifen in the treatment of juvenile breast hypertrophy during the brisk growth period may become a medical alternative to reconstructive surgery. © 2010 North American Society for Pediatric and Adolescent Gynecology.