Synthesis of Tricyclic Derivatives of Antitumor Alkaloid Ellipticine

Ergun Y., Gulle S., Bilici A. C., Gocmenturk M., Okay G.

ASIAN JOURNAL OF CHEMISTRY, cilt.22, sa.3, ss.1853-1858, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 3
  • Basım Tarihi: 2010
  • Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1853-1858
  • Anahtar Kelimeler: Carbazole, Ellipticine, Olivacine, Pyridocarbazoles
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The synthesis of tricyclic analogue of ellipticine, 3-[N-(2-hydroxyethyl)-aminomethyl]-4-methyl-9H-carbazole (10) has been achieved. In this study, new carbazole and tetrahydrocarbazole derivatives (3,4,7 and 9) have also been synthesized.