Fournier's gangrene: Evaluation of 68 patients and analysis of prognostic variables

Unallp H. R., Kamer E., Deric H., Atahan K., Ballcil U., Demirdoven C., ...More

JOURNAL OF POSTGRADUATE MEDICINE, vol.54, no.2, pp.102-105, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.4103/0022-3859.40775
  • Journal Name: JOURNAL OF POSTGRADUATE MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.102-105
  • Keywords: diabetes mellitus, Fournier's gangrene, infection, mortality, sepsis, MANAGEMENT, GENITALIA, SURVIVAL, PERINEUM
  • Dokuz Eylül University Affiliated: Yes

Abstract

Context: Fournier's gangrene (FG) is a rapidly progressing acute gangrenous infection of the anorectal and urogenital area. Aims: The objectives of this study were to investigate patients with FG and to determine risk factors that affect mortality. Settings and Design: Retrospective clinical study. Materials and Methods: Clinical presentations and outcomes of surgical treatments were evaluated in 68 patients with FG. Statistical Analysis Used: Chi-square, Student's t-test, and logistic regression test. Results: Mean age of patients was 54 and female-to-male ratio was 9:59. Among the predisposing factors, diabetes mellitus (DM) was the most common (n = 24, 35.3%), and sepsis on admission was detected in 31 (45.6%) and 15 (22.1%) patients, respectively. Seven (10.3%) patients died. Using logistic regression test, Fournier's Gangrene Severity Index (FGSI) > 9, DM and sepsis on admission were found as prognostic factors. Conclusions: FG has a high mortality rate, especially in patients with DM and sepsis. An FGSI value > 9 indicates high mortality rate.