Sulfasalazine-induced hypersensitivity syndrome in a 15-year-old boy associated with human herpesvirus-6 reactivation

Balci, DİDEM; Peker, Erdal; DURAN, NİZAMİ; Dogramaci, Cigdem

doi:10.1080/15569520802696250

Sulfasalazine-induced hypersensitivity syndrome in a 15-year-old boy associated with human herpesvirus-6 reactivation

Balci D. D., Peker E., DURAN N., Dogramaci C. A.

Cutaneous and Ocular Toxicology, vol.28, no.1, pp.45-47, 2009 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 28 Issue: 1
Publication Date: 2009
Doi Number: 10.1080/15569520802696250
Journal Name: Cutaneous and Ocular Toxicology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.45-47
Keywords: Sulfasalazine, drug-induced hypersensitivity syndrome, human herpesvirus-6 reactivation
Dokuz Eylül University Affiliated: No

Abstract

Drug-induced hypersensitivity syndrome (DIHS) is characterized by high fever, facial edema, diffuse maculopapular eruption, and multiorgan involvement. Human herpesvirus (HHV)-6 reactivation is an accepted criterion for the diagnosis of DIHS and has prognostic importance. We report a 15-year-old boy with juvenile rheumatoid arthritis who developed DIHS due to sulfasalazine, associated with reactivation of HHV-6. © 2009 Informa UK Ltd.