Structural dysconnectivity in offspring of individuals with bipolar disorder: The effect of co-existing clinical-high-risk for bipolar disorder

BORA İ. E., Can G., Zorlu N., Ulas G., Inal N., Ozerdem A.

JOURNAL OF AFFECTIVE DISORDERS, cilt.281, ss.109-116, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 281
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.jad.2020.11.122
  • Dergi Adı: JOURNAL OF AFFECTIVE DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, ASSIA, PASCAL, AgeLine, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
  • Sayfa Sayıları: ss.109-116
  • Anahtar Kelimeler: Bipolar disorder, High-risk, offspring, MRI, Connectivity, DTI, WHITE-MATTER INTEGRITY, BRAIN NETWORK ANALYSIS, RICH-CLUB, YOUNG-PEOPLE, METAANALYSIS, SCHIZOPHRENIA, CONNECTIVITY, CONNECTOME, HERITABILITY, INTEGRATION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Bipolar disorder (BD) might be associated in disturbances in brain networks. However, little is known about the abnormalities in structural brain connectivity which might be related to vulnerability to BD and predictive of the emergence of manic symptoms. No previous study has investigated the effect of subthreshold syndromes on structural dysconnectivity in offspring of parents with BD (BDoff).