A case of resistant pulmonary and cerebral aspergillosis succesfully treated with voriconazole

UÇAN E. S., AVKAN OĞUZ V., Gungor O., Gulsen A., Uggural Sezak N., TERTEMİZ K. C., ...More

TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX, vol.54, no.1, pp.75-79, 2006 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 1
  • Publication Date: 2006
  • Journal Name: TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.75-79
  • Keywords: Voriconazole, intracerebral aspergillosis, immunosupression
  • Dokuz Eylül University Affiliated: Yes

Abstract

Invasive pulmonary aspergillosis (IPA) is the most common fungal pulmonary infection in immunocompromised patients. In this disease, it is hard to diagnose, it's therapy process is variable and mortality is high. Prognosis is even worse in the cases which have cerebral aspergillosis. The patient was following up as a diagnosis of usual interstitial pneumonia and treating with corticosteroids and azothiopurine. Patient attented our clinic with headache and lose of vision. IPA and cerebral aspergillosis was the diagnosis as his examinations. Amphotericine B lipid complex treatment were given because of pulmonary and cerebral aspergillosis. Voriconazole was the second threapy because of the no response. Voriconazole is more effective in cerebral aspergillozis and treated this patient succesfully.