High Dose Omega-3 Fatty Acid Administration and Skeletal Muscle Protein Turnover in Maintenance Hemodialysis Patients

DEĞER, SERPİL; Hung, Adriana; Ellis, Charles; Booker, Cindy; Bian, Aihua; Chen, Guanhua; Abumrad, Naji; Ikizler, T.

doi:10.2215/cjn.04150415

High Dose Omega-3 Fatty Acid Administration and Skeletal Muscle Protein Turnover in Maintenance Hemodialysis Patients

DEĞER S. M., Hung A. M., Ellis C. D., Booker C., Bian A., Chen G., ...Daha Fazla

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, cilt.11, sa.7, ss.1227-1235, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 11 Sayı: 7
Basım Tarihi: 2016
Doi Numarası: 10.2215/cjn.04150415
Dergi Adı: CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1227-1235
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background and Objectives Protein energy wasting and systemic inflammation are prevalent in maintenance hemodialysis (MHD) patients. Omega-3 (omega-3) fatty acids have anti-inflammatory properties and have been shown to improve protein homeostasis. We hypothesized that administration of high-dose (2.9 g/d) omega-3 would be associated with decreased muscle protein breakdown in MHD patients with systemic inflammation.