Rat Model of Gluteus Medius Tendon Tear: Biomechanical and Histological Effects of Autologous Fascia Lata Augmentation


AYDEMİR S., AKIN E., Havitcioglu C., Ibrahim M. M., KARABAĞ Ü. A., Karabay U., ...Daha Fazla

American Journal of Sports Medicine, 2026 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1177/03635465261439946
  • Dergi Adı: American Journal of Sports Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CINAHL, MEDLINE
  • Anahtar Kelimeler: biomechanics, fascia lata autograft, gluteus medius tendon tear, histology, rat model
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Primary repair of full-thickness gluteus medius tears is challenging, particularly in retracted tears with poor tissue quality. Augmentation with autologous fascia lata may enhance repair strength and biologic healing. Purpose: To establish a gluteus medius tear detachment model in rats and to evaluate whether acute repair augmented with autologous fascia lata results in higher failure load and improved tendon-bone interface organization as compared with primary repair. Study Design: Controlled laboratory study. Methods: Forty adult female Sprague-Dawley rats were randomly assigned to 4 groups: intact control (group C), unrepaired tear (group 1), primary repair (group 2), and augmented repair with autologous fascia lata (group 3) (n = 6 for biomechanical testing, n = 4 for histological analysis per group). In groups 1 to 3, the gluteus medius tendon was detached from the greater trochanter. Group 1 underwent no repair. In groups 2 and 3, repair was performed acutely during the index procedure immediately after tendon detachment, using intraosseous tunnels and 5-0 Prolene sutures; in group 3, an autologous fascia lata graft was incorporated as an onlay augmentation. At 4 weeks, animals were euthanized for biomechanical and histological evaluation. Results: All tendons failed at the tendon-bone interface. Failure load was lower in group 1 (mean ± SD, 15 ± 6 N; P = .01) and group 2 (20 ± 4 N; P = .03) than in group C (29 ± 7 N), while group 3 (30 ± 7 N) did not differ from group C (P = .60). Group 3 had higher strength than groups 2 (P = .01) and 1 (P = .004). Histological scores were lowest in group 1 (3 ± 0.5) as compared with group C (8 ± 1; P = .01), group 2 (12 ± 2; P < .001), and group 3 (11 ± 1; P = .001), with no difference among groups C, 2, and 3 (P > .05). Conclusion: In a rat gluteus medius tendon detachment model, unrepaired detachment resulted in inferior biomechanical strength and histological healing at 4 weeks. Augmentation with autologous fascia lata improved biomechanical strength as compared with primary repair. Clinical Relevance: This rat model may be useful for preclinical evaluation of repair strategies for gluteus medius tears. Autologous fascia lata augmentation may offer biomechanical advantages over primary repair alone.