The prognostic importance of double-expressor subgroup and AID, UNG and mismatch repair protein expressions in diffuse large B-cell lymphomas

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Toper M. H., BOZKURT S., ELİBOL T., Tuglular T.

MARMARA MEDICAL JOURNAL, cilt.33, sa.2, ss.83-89, 2020 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5472/marumj.741651
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.83-89
  • Anahtar Kelimeler: Diffuse large B-cell lymphoma, Double-expressor lymphoma, MYC, BCL2, AID, Mismatch repair proteins, INDUCED CYTIDINE DEAMINASE, RITUXIMAB PLUS CYCLOPHOSPHAMIDE, IMMUNOHISTOCHEMICAL BIOMARKERS, MYC REARRANGEMENT, P53 EXPRESSION, C-MYC, SURVIVAL, GENE, BCL2, CLASSIFICATION
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The cases of diffuse large B-cell lymphoma, (DLBCL not otherwise specified (NOS)) which immunohistochemically exhibit MYC and BCL2 expressions arc defined as double-expressor lymphomas (DELs). This study aimed to assess the prognostic impact of DEL and the expressions of other proteins that may have role in tumorogenesis.