Neurocognitive heterogeneity in young offspring of patients with bipolar disorder: The effect of putative clinical stages

BORA İ. E., Can G., Ildiz A., Ulas G., HIDIROĞLU ONGUN C., Inal N. E., ...Daha Fazla

JOURNAL OF AFFECTIVE DISORDERS, cilt.257, ss.130-135, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 257
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jad.2019.07.015
  • Dergi Adı: JOURNAL OF AFFECTIVE DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.130-135
  • Anahtar Kelimeler: Bipolar disorder, Cognition, Offspring, Relatives, Subgroups, COGNITIVE IMPAIRMENT, FUNCTIONAL OUTCOMES, EUTHYMIC PATIENTS, MOOD DISORDERS, SCHIZOPHRENIA, PRODROME, MANIA, METAANALYSIS, IMPULSIVITY, DYSFUNCTION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Bipolar disorder (BD) is associated with significant cognitive heterogeneity. In recent years, a number of studies have investigated cognitive subgroups in BD using data-driven methods and found that BD includes several subgroups including a severely impaired and a neurocognitively intact cluster. Studies in offspring of BD (BDoff) are particularly important to establish the timing of emergence of cognitive subgroups but studies investigating cognitive heterogeneity in BDoff are lacking. Our aim was to investigate cognitive heterogeneity in BDoff and the relationship between cognitive heterogeneity and putative clinical stages of BD.