Female vulnerability for thyroid function abnormality in bipolar disorder: role of lithium treatment

Ozerdem A., Tunca Z., ÇIMRIN D., HIDIROĞLU ONGUN C., ERGÖR G.

BIPOLAR DISORDERS, cilt.16, sa.1, ss.72-82, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/bdi.12163
  • Dergi Adı: BIPOLAR DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.72-82
  • Anahtar Kelimeler: bipolar disorder, female, gender difference, lithium, thyroid function, HIGH-DOSE THYROXINE, TREATED PATIENTS, AUTOIMMUNE-THYROIDITIS, ANTITHYROID ANTIBODIES, REFERENCE INTERVALS, NATIONAL-HEALTH, UNITED-STATES, DEPRESSION, HYPOTHYROIDISM, THYROTROPIN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

BackgroundPrevious studies have provided evidence of subtle thyroid hormone metabolism abnormalities in patients with mood disorders. Although these studies are informative, the precise role of the hypothalamic-pituitary-thyroid axis in bipolar disorder, especially in women, remains unclear. We sought to further corroborate thyroid function in patients with bipolar disorder in comparison to patients with other psychiatric, as well as non-psychiatric, diagnoses.