Female vulnerability for thyroid function abnormality in bipolar disorder: role of lithium treatment


Ozerdem A., Tunca Z., ÇIMRIN D., HIDIROĞLU ONGUN C., ERGÖR G.

BIPOLAR DISORDERS, vol.16, no.1, pp.72-82, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1111/bdi.12163
  • Journal Name: BIPOLAR DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.72-82
  • Keywords: bipolar disorder, female, gender difference, lithium, thyroid function, HIGH-DOSE THYROXINE, TREATED PATIENTS, AUTOIMMUNE-THYROIDITIS, ANTITHYROID ANTIBODIES, REFERENCE INTERVALS, NATIONAL-HEALTH, UNITED-STATES, DEPRESSION, HYPOTHYROIDISM, THYROTROPIN
  • Dokuz Eylül University Affiliated: Yes

Abstract

BackgroundPrevious studies have provided evidence of subtle thyroid hormone metabolism abnormalities in patients with mood disorders. Although these studies are informative, the precise role of the hypothalamic-pituitary-thyroid axis in bipolar disorder, especially in women, remains unclear. We sought to further corroborate thyroid function in patients with bipolar disorder in comparison to patients with other psychiatric, as well as non-psychiatric, diagnoses.