Levels of interleukin-6 (IL-6) and its soluble (sIL-6R) in familial Mediterranean fever (FMF) patients and their first degree relatives

Oktem S., Yavuzsen T., Sengul B., Akhunlar H., Akar S., Tunca M.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.22, sa.4, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 4
  • Basım Tarihi: 2004
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: familial Mediterranean fever (FMF), IL-6, sIL-6R, FMF carriers
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective. Familial Mediterranean Fever (FMF) is a hereditary disease characterized by recurrent inflammatory attacks. A subclinical inflammation may persist in periods between the attacks and heterozygotes may have higher than normal levels of acute phase proteins. We investigated the levels of interleukin-6 (IL-6) and its soluble receptor (sIL-6R) in FMF patients and their obligatory carrier relatives.