Increased hippocampal volumes in lithium treated adolescents with bipolar disorders: A structural MRI study

BAYKARA H. B., Inal-Emiroglu N., KARABAY N., Cakmakci H., Cevher N., ŞENTÜRK PİLAN B., ...More

JOURNAL OF AFFECTIVE DISORDERS, vol.138, no.3, pp.433-439, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 138 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.jad.2011.12.047
  • Journal Name: JOURNAL OF AFFECTIVE DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.433-439
  • Keywords: Bipolar disorder, Hippocampus, MRI, Adolescence, TEMPORAL-LOBE STRUCTURES, GRAY-MATTER VOLUME, MOOD STABILIZERS, EARLY-ONSET, MAJOR DEPRESSION, AMYGDALA VOLUME, SCHIZOPHRENIA, ADULTS, NEUROGENESIS, ILLNESS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Structural neuroimaging studies in bipolar disorder (BD) have consistently identified several anatomical abnormalities in many brain areas related to mood regulation. Hippocampus is one of the key components of emotional regulatory networks in the brain. Evidence about hippocampal changes in BD is quite limited and inconsistent particularly for adolescent onset BD. It is aimed to compare hippocampus volumes of euthymic BD-I adolescents with healthy controls using structural MRI.