Penetration of meropenem and cefepim into pancreatic tissue during the course of experimental acute pancreatitis

Saglamkaya U., Mas M., Yasar M., Simsek I., Mas N. N., Kocabalkan F.

PANCREAS, vol.24, no.3, pp.264-268, 2002 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2002
  • Doi Number: 10.1097/00006676-200204000-00009
  • Journal Name: PANCREAS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.264-268
  • Keywords: meropenem, cefepim, acute pancreatitis, antibiotics, penetration, ACUTE NECROTIZING PANCREATITIS, ANTIBIOTIC-PROPHYLAXIS, INFECTION, MODEL, RAT, TOLERANCE, SAFETY
  • Dokuz Eylül University Affiliated: No

Abstract

Introduction: Recent data from experimental and clinical studies suggest that the antibiotics showing good penetration into the pancreas may reduce mortality by preventing pancreatic infection, which is the most important prognostic factor in acute pancreatitis.