Detection of toxin production in Clostridium difficile strains by three different methods


Yucesoy M., McCoubrey J., Brown R., Poxton I.

CLINICAL MICROBIOLOGY AND INFECTION, vol.8, no.7, pp.413-418, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 7
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1469-0691.2002.00440.x
  • Journal Name: CLINICAL MICROBIOLOGY AND INFECTION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.413-418
  • Keywords: Clostridium difficile, toxin A, toxin B, immunoassay, antibiotic-associated diarrhoea, tissue culture, cytopathic effect, MULTICENTER EVALUATION, ENZYME-IMMUNOASSAY, CYTOTOXICITY ASSAY, DIAGNOSIS, CULTURE, PROTEINS, DIARRHEA
  • Dokuz Eylül University Affiliated: No

Abstract

Objective To compare two immunoassays for detection of toxins produced in vitro by isolates of Clostridium difficile with the standard tissue culture assay, to help in the diagnosis of C. difficile -associated diarrhoea.