Long-standing fever and Angelman syndrome: Report of two cases

YİŞ U., Giray Ö., Kurul S. H., BORA E., ÜLGENALP A., Ercal D., ...More

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, vol.44, no.5, pp.308-310, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1440-1754.2008.01302.x
  • Journal Name: JOURNAL OF PAEDIATRICS AND CHILD HEALTH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.308-310
  • Keywords: Angelman syndrome, fever, hypothalamic dysfunction, PRADER-WILLI-SYNDROME
  • Dokuz Eylül University Affiliated: Yes

Abstract

An 8-month-old girl and a 20-month-old boy who presented with motor and developmental delay and long-standing fever are presented. The patients were diagnosed as Angelman syndrome with fluorescence in situ hybridization (FISH) analysis. Despite extensive clinical and laboratory examinations, no inflammatory or infectious origin for the fever was found. It was considered that the long-standing fever observed in these cases was due to hypothalamic dysfunction for thermoregulation.