Therapeutic plasma exchange in amitriptyline intoxication: Case report and review of the literature

SARI İ., Turkcuer I., Erurker T., Serinken M., Seyit M., Keskin A.

TRANSFUSION AND APHERESIS SCIENCE, cilt.45, sa.2, ss.183-185, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 45 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.transci.2011.07.015
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.183-185
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Severe amitriptyline poisoning results in cardiac and neurological toxicity and continues to be a leading cause of significant morbidity and mortality both in children and adults. We present a case of severe amitriptyline poisoning successfully treated with plasma exchange. Due to high plasma protein binding property of amitriptyline, plasma exchange therapy should be considered in cases of severe amitriptyline intoxication as a life saving therapeutic modality. (C) 2011 Elsevier Ltd. All rights reserved.