preventing delirium. This research; It was conducted to examine the knowledge, attitudes and practices of nurses and physicians working in intensive care units regarding delirium management. Methods: The research was conducted in a descriptive design in three university hospitals in Izmir. The sample of the research consisted of 175 healthcare professionals working in the intensive care units of the hospitals where the research was conducted and who agreed to participate in the research. The data were collected with data collection forms consisting of a total of four sections, 47 questions, including a questionnaire on sociodemographic characteristics, a questionnaire on knowledge, attitudes and practices regarding delirium. Results: It was determined that the average age of the healthcare professionals participating in the research was 30.81±3.88, 24% were women, 66.9% had received training on delirium, and 151 (86.3%) were not able to make diagnoses. It was determined that as the knowledge score of intensive care healthcare professionals increased, their practice score increased, and as the practice score increased, their attitude score increased. A statistical significance was found between knowledge and application scores. Physicians' knowledge score was higher (p= 0.02), and nurses' practice score was higher (p=0.028). Conclusion: As a result of the research, it was determined that as the knowledge score of intensive care healthcare professionals increased, their practice score increased, and as the practice score increased, their attitude score increased. In this regard, it is recommended to provide in-service training on delirium diagnosis in intensive care patients in hospitals and to develop delirium diagnosis standards for diagnosis. Keywords: Knowledge, Delirium, Health Care Professional, Attitude, Practice.