The effects of heparin coated circuits on pulmonary injury - A clinical study

Kazaz H., Oto O., Sariosmanoglu N., Hazan E.

JOURNAL OF CARDIOVASCULAR SURGERY, vol.44, no.5, pp.611-615, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 5
  • Publication Date: 2003
  • Journal Name: JOURNAL OF CARDIOVASCULAR SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.611-615
  • Keywords: cardiopulmonary bypass, coated materials, biocompatible, heparin, complement activation, lung, physiopathology, CARDIOPULMONARY BYPASS, COMPLEMENT ACTIVATION, EXTRACORPOREAL-CIRCULATION, GRANULOCYTE ACTIVATION, INFLAMMATORY RESPONSE, REDUCED COMPLEMENT, OXYGENATOR, C5A
  • Dokuz Eylül University Affiliated: No

Abstract

Aim Heparin-coated circuits have dramatic effects on the coagulation cascade, but their role on complement activation has not been clearly defined. in this clinical study the effect of heparin-coated circuits on static lung compliance and pulmonary vascular resistance is described.