Multicentric Plasma Cell Type of Castleman Disease in a Child: Difficulty in Diagnosis and Treatment

Karapinar T. H., TÜFEKÇİ Ö., Gozmen S., YILMAZ Ş., Irken G., ÖREN H.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.35, sa.7, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 7
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1097/mph.0b013e31829cdd2a
  • Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Castleman disease, childhood, plasma cell, LYMPH-NODE HYPERPLASIA, MANIFESTATION, TOCILIZUMAB
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Multicentric plasma cell variant of Castleman disease (CD) has rarely been reported and the optimal therapeutic approach is unknown, especially in childhood. In this case report, we discuss the case of a 7-year-old boy with multicentric plasma cell variant of CD, who presented with cervical lymphadenopathies, autoimmune hemolytic anemia, bone marrow insufficiency, pulmonary, renal, hepatic, and gastrointestinal involvement, emphasizing the difficulty in diagnosis and treatment approach.