Different maternal serum hCG levels in pregnant women with female and male fetuses: does fetal hypophyseal adrenal gonadal axis play a role?

Gol M., ALTUNYURT S., Cimrin D., Guclu S., Bagci M., Demir N.

JOURNAL OF PERINATAL MEDICINE, cilt.32, sa.4, ss.342-345, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1515/jpm.2004.064
  • Dergi Adı: JOURNAL OF PERINATAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.342-345
  • Anahtar Kelimeler: fetal, gender, hCG, hormones, maternal
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Fetal gender has a significant effect on maternal and cord blood hCG levels, particularly during the last trimester of the pregnancy. However, the reason for this difference is obscure. The aim of the present study was to investigate whether term fetal hypophyseal adrenal gonadal axis differs between female and male fetuses thereby causing different hCG levels. The study consisted of 60 women with singleton pregnancies in the third trimester. Thirtyone pregnant women were carrying female fetuses, whereas 29 were carrying male. Human chorionic gonadotropin (hCG), estradiol, progesterone, testosterone, dehydroepiandrosteronsulfate (DHEAS), prolactin and growth hormone levels were measured in maternal serum and umbilical cord blood.