Differences in Poly(ADP-ribose) Polymerase1-(PARP1-) and Proliferative Cell Nuclear Antigen (PCNA) Immunoreactivity in Patients Who Experienced Successful and Unsuccessful Microdissection Testicular Sperm Extraction Procedures

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Akarsu S., Buke B., GÜRGEN S. G., Akdemir S., Gode F., Bicer M., ...More

UROLOGY JOURNAL, vol.14, no.5, pp.5018-5022, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 14 Issue: 5
• Publication Date: 2017
• Journal Name: UROLOGY JOURNAL
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.5018-5022
• Keywords: Azoospermia, Micro-Tese, PCNA, PARP-1, NONOBSTRUCTIVE AZOOSPERMIA, OXIDATIVE STRESS, DNA-DAMAGE, APOPTOSIS, SPERMATOGENESIS, DEATH, FRAGMENTATION, FERTILIZATION, SPERMATOGONIA, EXPRESSION
• Dokuz Eylül University Affiliated: No

Abstract

Purpose: The aim of this study is to evaluate expression of deoxyribonucleic acid (DNA) synthesis and repair markers in testicular tissues of azoospermic men in whom sperm retrieval could and could not be achieved as a result of microdissection testicular sperm extraction (micro-TESE) procedure.