Adherence to guideline-directed medical treatments in heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy

Savarese, Gianluigi; Lindberg, Felix; Cannata, Antonio; Adamo, Marianna; Ambrosio, Giuseppe; Ameri, Pietro; Anker, Markus; Bäck, Magnus; Bayes-Genis, Antoni; Ben Gal, Tuvia; Braunschweig, Frieder; Chioncel, Ovidiu; D'Elia, Emilia; El-Tamimi, Hassan; Filippatos, Gerasimos; Girerd, Nicolas; Hill, Loreena; Jankowska, Ewa; Khunti, Kamlesh; Lewis, Basil; Moura, Brenda; Amir, Offer; Paolillo, Stefania; Piepoli, Massimo; Shehab, Abdulla; Simpson, Maggie; Skouri, Hadi; Stolfo, Davide; Tocchetti, Carlo; Vitale, Cristiana; Volterrani, Maurizio; von Haehling, Stephan; Wassmann, Sven; Yilmaz, MEHMET; Kaski, Juan; Dobrev, Dobromir; Metra, Marco; Rosano, Giuseppe

doi:10.1002/ejhf.70090

Adherence to guideline-directed medical treatments in heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy

Savarese G., Lindberg F., Cannata A., Adamo M., Ambrosio G., Ameri P., ...Daha Fazla

European Journal of Heart Failure, 2025 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2025
Doi Numarası: 10.1002/ejhf.70090
Dergi Adı: European Journal of Heart Failure
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
Anahtar Kelimeler: Heart failure, Adherence, Guidelines, Polypill, Fixed-dose combinations, Digital, Education, Multidisciplinary
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline-directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non-adherence represents a critical barrier limiting real-world efficacy of GDMT. This scientific statement aims to provide a comprehensive framework for understanding, measuring, and addressing medication non-adherence in HF management across diverse healthcare settings. Addressing medication non-adherence requires systematic, multifaceted approaches targeting individual patient barriers while implementing system-level interventions. Polypills, digital monitoring platforms, enhanced patient education and empowerment, and multidisciplinary care models represent promising strategies to optimize therapeutic adherence and improve clinical outcomes in HF management.