urginea maritima (squill) toxicity

Tunçok Y., Kozan O., Çavdar C., Guven H., Fowler J.

Clinical Toxicology, cilt.33, sa.1, ss.83-86, 1995 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 1995
  • Doi Numarası: 10.3109/15563659509020221
  • Dergi Adı: Clinical Toxicology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.83-86
  • Anahtar Kelimeler: SQUILL, URGINEA MARITIMA, CARDIAC GLYCOSIDES, POISONING, FAB ANTIBODY FRAGMENTS, DIGOXIN, INTOXICATION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

A 55 year-old female ingested two bulbs of Urginea maritime (squill) plant as a folk remedy for her arthritic pains. Her past history was significant for Hashimoto thyroiditis and she was hypothyroid upon presentation. Subsequent effects resembling those seen with cardiac glycoside intoxication included nausea, vomiting, seizures, hyperkalemia, atrioventricular block and ventricular arrhythmias resembling digitalis toxicity. A serum digoxin level by an enzyme immunoassay method was 1.59 ng/mL. Despite supportive treatment and pacing, the patient expired from ventricular arrhythmias 30 h after ingestion. Squill has been recognized since antiquity for the clinical toxicity of its cardiac glycosides, but this appears to be the first report of a fatality since 1966. © 1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.