Energy window optimization in bremsstrahlung imaging after Yttrium-90 microsphere therapy


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Kayaş Demirtaş C., Can M., Karadeniz Ö., Vupa Çilengiroğlu Ö., Ertay T., Çapa Kaya G.

BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, cilt.10, sa.2, 2024 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1088/2057-1976/ad25ba
  • Dergi Adı: BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Compendex, EMBASE, INSPEC, MEDLINE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

In imaging of Yttrium-90 patients treated hepatic primary and metastatic cancers, bremsstrahlung photons produced in a wide energy range is used. However, the image quality depends on acquisition energy window. This research aimed energy window optimization for Yttrium-90 bremsstrahlung imaging and 48 patients with various types of cancer received radioembolization therapy were investigated. Patients were imaged using a GE Healthcare Optima NM/CT 640 series gamma camera system with a medium energy general-purpose (MEGP) collimator and planar images were acquired with 8 different energy windows in the 55-400 keV energy range. The data set, formed with the % FOV, contrast, and spatial resolution of image quality parameters calculated from these images, was statistically examined with ANOVA and Tukey tests. According to the visual evaluations and ANOVA/Tukey test results, it was statistically concluded that energy window of 90-110 keV is the optimal energy window while 60-400 keV energy ranges show the lowest image quality for Y-90 bremsstrahlung imaging.