Biomedical physics & engineering express, 2024 (ESCI)
In imaging of Yttrium-90 patients treated hepatic primary and metastatic cancers,
bremsstrahlung photons produced in a wide energy range is used. However, the image quality
depends on acquisition energy window. This research aimed energy window optimization for
Yttrium-90 bremsstrahlung imaging and 48 patients with various types of cancer received
radioembolization therapy were investigated. Patients were imaged using a GE Healthcare
Optima NM/CT 640 series gamma camera system with a medium energy general-purpose
(MEGP) collimator and planar images were acquired with 8 different energy windows in the
55-400 keV energy range. The data set, formed with the % FOV, contrast, and spatial
resolution of image quality parameters calculated from these images, was statistically
examined with ANOVA and Tukey tests. According to the visual evaluations and
ANOVA/Tukey test results, it was statistically concluded that energy window of 90-110 keV
is the optimal energy window while 60–400 keV energy ranges show the lowest image quality
for Y-90 bremsstrahlung imaging