Contingent Negative Variation Is Associated with Cognitive Dysfunction and Secondary Progressive Disease Course in Multiple Sclerosis

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UYSAL U., Idiman F., Idiman E., ÖZAKBAŞ S., Karakas S., Bruce J.

JOURNAL OF CLINICAL NEUROLOGY, vol.10, no.4, pp.296-303, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.3988/jcn.2014.10.4.296
  • Journal Name: JOURNAL OF CLINICAL NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.296-303
  • Keywords: relapsing-remitting multiple sclerosis, secondary progressive multiple sclerosis, contingent negative variation cognitive dysfunction, event-related potentials, neuropsychological test
  • Open Archive Collection: AVESIS Open Access Collection
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background and Purpose The relationship between contingent negative variation (CNV), which is an event-related potential, and cognition in multiple sclerosis (MS) has not been examined previously. The primary objective of the present study was thus to determine the association between CNV and cognition in a sample of MS patients.