Akademik Veri Yönetim Sistemi
The Atlantic Journal of Medical Science and Research, cilt.4, sa.4, ss.96-101, 2024 (Hakemli Dergi)
Aim: Atopic dermatitis (AD) is a chronic, itchy inflammatory skin disease. This study aimed to examine the clinical features, investigate laboratory test results, and evaluate disease prognosis using allergy tests in patients with AD.
Materials and Methods: This retrospective study analyzed patient demographics, clinical characteristics, and laboratory data, including serum eosinophils, serum total IgE, other immunoglobulin (Ig) levels, skin prick test results, and patch test results.
Results: A total of 564 patients were diagnosed with AD, of whom 343 (60.8%) were boys. Skin prick tests were positive in 138 (35.1%) patients. Eosinophilia was more common in patients with food sensitivity within the first year of life (p<0.001). Patch test hypersensitivity was observed in half of the 32 patients tested. During follow-up, tolerance developed in 67.4% of 123 patients. Girls developed tolerance to foods earlier than boys (p=0.005). Sensitivity to inhaled allergens was higher in patients who developed tolerance after 2 years of age compared to those who developed tolerance before 2 years (p=0.001).
Conclusion: Elevated serum eosinophil counts in AD patients within the first year of life may indicate a higher risk of food sensitivity. Atopy patch tests may help clarify food allergies, and clinicians should consider that AD patients are at risk for aeroallergen sensitivities in addition to food sensitivities.