Human Epidermal Growth Factor Receptor 2 Overexpression in Micropapillary and Other Variants of Urothelial Carcinoma

Behzatoglu K., YÖRÜKOĞLU K., Demir H., Bal N.

EUROPEAN UROLOGY FOCUS, vol.4, no.3, pp.399-404, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.1016/j.euf.2016.06.007
  • Journal Name: EUROPEAN UROLOGY FOCUS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.399-404
  • Keywords: HER2, Immunohistochemistry, Urothelial carcinoma, Micropapillary, Variants, Targeted therapy, HER2 GENE AMPLIFICATION, BLADDER-CANCER, BREAST-CANCER, TARGETED THERAPY, PATTERN, SURVIVAL
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Human epidermal growth factor receptor 2 (HER2) protein overexpression or gene amplification has been shown in urothelial bladder cancer. This could be helpful when using targeted anti-HER2 therapy on these tumors.