Research Information System
Çocuk Enfeksiyon Dergisi, vol.18, no.2, pp.119-126, 2024 (ESCI)
Group A streptococci (GAS) are one of the leading causes of invasive bacterial diseases worldwide, and the incidence of invasive GAS (iGAS) infections has been increasing worldwide for the last 20 years. Epidemiological data in developing countries are very limited, as these infections are only required to be reported in a limited number of European countries. Although group A streptococci are universally susceptible to β-lactam antibiotics, resistance to penicillin alternative treatment regimens (macrolide and lincosamide antibiotics) as well as the emergence of subclinical β-lactam resistence is of concern. Despite the vaccine studies that have been going on for a century, there is no effective vaccine yet.