Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia-reperfusion injury in rats

Bagcik E., ÖZKARDEŞLER S., BOZTAŞ N., Ergur B. U., Akan M., Guneli M. E., ...More

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.64, no.6, pp.382-390, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1016/j.bjan.2014.01.002
  • Journal Name: REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.382-390
  • Keywords: kidney, Ischemia-reperfusion injury, Dexrnedetomidine, Caspase-3, Ischemic preconditioning, Apoptosis, DELAYED GRAFT FUNCTION, MEDICAL PROGRESS, KIDNEY, FAILURE, CLONIDINE, SURGERY, S(+)-KETAMINE, EXPRESSION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background and objectives: The aim of this study was to evaluate the effects of remote ischemic preconditioning by brief ischemia of unilateral hind limb when combined with dexmedetomidine on renal ischemia-reperfusion injury by histopathology and active caspase-3 immunoreactivity in rats.