Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia-reperfusion injury in rats

Bagcik, Emine; ÖZKARDEŞLER, SEVDA; BOZTAŞ, NİLAY; Ergur, Bekir; Akan, Mert; Guneli, MEHMET; ÖZBİLGİN, ŞULE

doi:10.1016/j.bjan.2014.01.002

Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia-reperfusion injury in rats

Bagcik E., ÖZKARDEŞLER S., BOZTAŞ N., Ergur B. U., Akan M., Guneli M. E., ...Daha Fazla

REVISTA BRASILEIRA DE ANESTESIOLOGIA, cilt.64, sa.6, ss.382-390, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 64 Sayı: 6
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.bjan.2014.01.002
Dergi Adı: REVISTA BRASILEIRA DE ANESTESIOLOGIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.382-390
Anahtar Kelimeler: kidney, Ischemia-reperfusion injury, Dexrnedetomidine, Caspase-3, Ischemic preconditioning, Apoptosis
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background and objectives: The aim of this study was to evaluate the effects of remote ischemic preconditioning by brief ischemia of unilateral hind limb when combined with dexmedetomidine on renal ischemia-reperfusion injury by histopathology and active caspase-3 immunoreactivity in rats.