Bell's palsy and choreiform movements during peginterferon α and ribavirin therapy

Barut S., Karaer H., Oksuz E., Eken A. G., Basak A. N.

WORLD JOURNAL OF GASTROENTEROLOGY, cilt.15, sa.29, ss.3694-3696, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 29
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3748/wjg.15.3694
  • Dergi Adı: WORLD JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3694-3696
  • Anahtar Kelimeler: Interferon alpha, Bell's palsy, Neurotoxicity, Huntington's disease
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Neuropsychiatric side effects of long-term recombinant interferon-alpha therapy consist of a large spectrum of symptoms. In the literature, cranial neuropathy, especially Bell's palsy, and movement disorders, have been reported much less often than other neurotoxic effects. We report a case of Bell's palsy in a patient with chronic hepatitis C during peginterferon-alpha and ribavirin therapy. The patient subsequently developed clinically inapparent facial nerve involvement on the contralateral side and showed an increase in choreic movements related to Huntington's disease during treatment. (C) 2009 The WJG Press and Baishideng. All rights reserved.