Asymmetric transfer hydrogenation reaction in water: Comparison of chiral proline amide/amine ruthenium(II) complexes

DENİZALTI S., Mercan D., Sen B., Gokce A. G., Cetinkaya B.

JOURNAL OF ORGANOMETALLIC CHEMISTRY, cilt.779, ss.62-66, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 779
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jorganchem.2014.12.023
  • Dergi Adı: JOURNAL OF ORGANOMETALLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.62-66
  • Anahtar Kelimeler: L-proline, Ruthenium, Asymmetric transfer hydrogenation, AROMATIC KETONES, ENANTIOSELECTIVE REDUCTION, PROCHIRAL KETONES, MICHAEL ADDITION, DIAMINE LIGANDS, ALDOL REACTION, ORGANOCATALYSTS, PHOSPHORAMIDES, ALLYLATION, ALDEHYDES
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Chiral proline amide/amine ligands (2, 3), synthesized by multi-step reaction starting from L-proline (1), were evaluated as catalyst generated in situ from [RuCl2(p-cymene)](2) for asymmetric transfer hydrogenation of aromatic ketones in the presence of sodium formiate and sodium dodecyl sulfate (SDS). The results revealed that efficiencies and enantioselectivities strongly depend on the N-substituents. (C) 2014 Elsevier B.V. All rights reserved.