Akademik Veri Yönetim Sistemi
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, cilt.64, sa.9, ss.465-473, 2015 (SCI-Expanded, Scopus)
The authors report herein in vitro antibacterial property and osteoblast biocompatibility of electrospun Ag doped HAp/PHBV (Ag-HAp/PHBV) composite nanofibers as an osteoconductive and antibacterial material for bone tissue engineering applications. Ag-HAp powders were synthesized and stable composite suspensions of Ag-HAp/PHBV were prepared with the aid of a cationic surfactant DTAB for the electrospinning process. Continuous and uniform composite nanofibers were generated within a diameter range of 400-900 nm. Obtained nanocomposite scaffolds provide a favorable environment for bonemineralization, SaOS-2 osteoblastic cell attachment and growth as well as they present antibacterial activity against E. coli and S. aureus bacteria without any noticeable cytotoxic effect.